Eosinophil Morphology

Effects of eosinophil granule proteins on human corneal epithelial cell viability and morphology.

PURPOSE There is mounting evidence that eosinophil granule proteins may cause tissue injury during allergic inflammation of the eye. Therefore, the authors investigated the in vitro effects of human eosinophil major basic protein (MBP), eosinophil cationic protein (ECP), eosinophil peroxidase (EPO), and eosinophil-derived neurotoxin (EDN) on cultured human corneal epithelial cell viability and ...

The Eosinophil

The literature on the eosinophil is vast. In the preface to this book the authors refer to a review published in 1914 which cited almost 3,000 references. That this and much subsequent work has contributed so little to our u.nderstanding of the eosinophil is largely due to the fact that techniques available to study haematogenous cells were inappropriate to the fundamental problems of their ori...

Eosinophil Lung

Eosinophil cationic protein is not only a distinctive eosinophil protein

We read with interest the article by Qiu et al (Thorax 2007;62:475–82). In this paper, neutrophils and eosinophils were identified using mouse anti-human neutrophil elastase and anti-eosinophil cationic protein (ECP), both monoclonal antibodies (mAbs). mAbs against ECP have been used to detect total eosinophils, but immunostaining techniques evidenced that the number of ECP cells was higher tha...

Eosinophil cationic protein is not only a distinctive eosinophil protein

We read with interest the article by Qiu et al (Thorax 2007;62:475–82). In this paper, neutrophils and eosinophils were identified using mouse anti-human neutrophil elastase and anti-eosinophil cationic protein (ECP), both monoclonal antibodies (mAbs). mAbs against ECP have been used to detect total eosinophils, but immunostaining techniques evidenced that the number of ECP cells was higher tha...